Some insulating materials like skin and bones

EMT may act in depression by balancing the inter-hemispheric asymmetry between the left and right prefrontal lobe and observed in major depression.
This concept, TMS can be considered as a non-convulsive treatment for pharmacologically-resistant depression, which may avoid the use of Electroconvulsive therapy (ECT).
Several studies in animals and humans were conducted to evaluate the effectiveness of TMS in the treatment of depression.
 Such studies, with some surprising results demonstrate that TMS is a promising tool.
 Nevertheless, the EMT is still experimental, still waiting for further studies to be validated, however, in the future, the EMT can become a powerful tool in diagnosis and therapy in neuropsychiatry.
 The authors' goal in this article is to review the basic principles of TMS and discuss the results of studies on the use of this technique in the treatment of depression. http://www.hypermuscles.com/f89/exercise-eliminate-stagnation-lymph-6914/#post33056 INTRODUCTION
The human cortex can be stimulated by a non-invasive and virtually painless technique in conscious humans using a pulsed magnetic field.
This technique, called magnetic stimulation (TMS or Tran cranial Magnetic Stimulation - TMS), is based on a variable magnetic field.
A small coil that receives an extremely potent alternating electrical current is placed on the human skull in the region of the cortex. Constant change of the orientation of the electric current in the coil is capable of generating a magnetic field that passes through some insulating materials like skin and bones, generating electrical current inside the skull, which is able to be focused and restricted to small areas depending geometry and shape of the coil [Halle, 2000]. http://forum.predatornutrition.com/forum/nutrition/how-much-protein-do-we-need/#p25483

Depressed patients showed a significant improvement

Eight patients with unit polar depression and six healthy subjects underwent stimulation with the following paradigms: five sessions of 20 stimuli at 0.5 Hz, separated by a minute, for a total of 100 stimuli per day for eight sessions.
Depressed patients showed a statistically significant improvement in both scales applied
Inventory Beck Depression and Hamilton-D Klein et al [1999,] performed a similar protocol but with a larger sample (70 patients) divided into two groups: group treatment that received TMS over the right frontal lobe with the intensity of 110% LM in 10 sessions at 1 Hz with 120 stimuli each session, and the group with sham TMS. http://www.naturalmuscle.co.uk/forum/index.php?topic=2261.0
Patients who received TMS had great improvement in scores of depression scales compared with the placebo group.
Seventeen of the 32 patients in the real TMS group and only 32 in eight patients in the placebo group improved more than 50% in the Hamilton-D scale.
Increased activity in the right prefrontal lobe may be the one responsible for the decreased activity of the wolf left prefrontal depression.
One of the advantages of inhibiting the right frontal lobe with rather low TMS stimulation of the left prefrontal lobe with high frequency often is safety.
 It reduced the likelihood of low frequency TMS cause seizures, despite the high-frequency TMS still be acceptably safe [Ember et al, 1998]. http://www.hypermuscles.com/f89/how-gain-muscle-mass-using-forearms-rod-6913/#post33055
The effects of low frequency TMS in the right prefrontal cortex in major depression and psychotic are still unknown. These studies support the paradigm of unbalance of the prefrontal lobe in major depression. COULD INDUCE EMTR CRISIS OF BIPOLAR MANIA IN PATIENTS?

Treating major depression and psychosis

On the other hand, in the group of non-psychotic patients the response was very similar in both treatments (CET - 6 in 10 patients with good response, TMS - 7 in 11 patients with good response).
 The authors concluded that TEC is clearly superior to treat DM with psychosis and that TMS has a similar response to ECT for the treatment of DM patients with psychosis.
 They also concluded that TMS for four weeks has greater efficacy. This result is opposite to that published by Paschal-Leone et al in 1996 showed good response with the use of TMS for the treatment of DM with depression.  http://www.bodyactive-nation.co.uk/forum/Exercises/5446-The-Best-Biceps-Exercise-You-re-Not-Doing#p69715
The reason may be due to the fact that Paschal-Leone et al used different paradigms and outpatients in TMS.
Because the patients in the study by Pascal-Leone et al remain in outpatient treatment for five months, they should be considered substantially less sick than patients with diabetes with acute psychosis who participated in the study Gnaws et al.
Added to the fact that the study of Grays et al had an unblended trial and there was no placebo group.
 Another important aspect that should be addressed in the treatment of depression and TMS inhibitory role via inter hemispheric corpus callous [Moore, 2000].
Meknes et al [1999] demonstrated that inhibitory TMS applied to the right prefrontal cortex produced a significant antidepressant effect, in contrast to the excitement of the left frontal lobe with high-frequency TMS. They conducted a pilot TMS stimulation of the right prefrontal lobe case-control study. http://www.naturalmuscle.co.uk/forum/index.php?topic=2261.0

Psychotic depression and similar efficacy

For the authors, the placebo response could be due to significant clinical contact and activity involved in the study (daily sessions), although this is an amazing fact when considering the refractory nature of depression.
Alternatively, the EMT placebo may have some degree of action, even considering that the stimulus caused by this form is much smaller than the traditional way. 3) http://forums.moneysavingexpert.com/showthread.php?t=4744771 Other Education: Other studies have been conducted to evaluate the effects of TMS in depression three of them must be considered.
Et al [2000] comparing the effects of ECT with TMS obtained a better effect of the first from the second to the treatment of psychotic depression and similar efficacy between the two methods for the treatment of non-psychotic depression.
Meknes et al [1999] obtained good results in the treatment of patients with depression by stimulating the right with low frequency TMS prefrontal cortex (maybe due to some inhibitory mechanism)
Klein et al [1999,] in a similar study confirmed the antidepressant effect of low frequency TMS (1 Hz) on the right.
 Prefrontal cortex Gauss et al [2000], in an open study comparing the effects of TMS and TEC, studied 40 patients with major depression (MD) unresponsive to antidepressant treatment with DM or psychosis. The treated patients received 9.6 http://www.bodyactive-nation.co.uk/forum/Exercise-Programs-Training-Discussion/5259-5-general-training-Tips#p69714 TEC  sessions on average. RTMS was applied to 90% LM (400-1200 pulses per day 10Hz) five times a week for 4 weeks.
The psychotropic medication was continued as pretreatment. In the group of psychotic patients, treatment with TEC was significantly more effective in relation to TMS in another group.

Antidepressant medications were maintained at a stable dose

Antidepressant medications were maintained at a stable dose. The stimulation was performed over the left prefrontal cortex. Patients received 250 pulses for five days at an intensity of 90% LM.
 Only the group that received low frequency TMS showed a small improvement in scores on the Hamilton scale - decrease of 19%.
The difference between these studies poor effects of high-frequency TMS to the previous best results could be due to methodological differences, i.e. fewer stimuli / day and total treatment time compared to previous studies with high frequency [Paschal-Leone et al, 1996, George et al, 1997; Trigs et al, 1999].  hunainnaeem01: http://www.fragrantica.com/board/viewtopic.php?pid=1665792#p1665792Another difference was the quality of the sample: Pad berg et al used very severe patients with pharmacologically resistant depression (3 patients had tried medication unsuccessfully), while in other studies such as the one conducted by Look et al [1999], patients had tried Only one drug without result.
 Look et al [1999], in a double blind study with 18 patients with pharmacologically resistant severe depression found different results from those previously published (discussed above).
 Patients were randomly divided into two groups: TMS of the left doors lateral prefrontal cortex (1500 pulses, 110Hz, 110% LM) and sham TMS.
 They showed a significant linear improvement after 2 weeks of treatment in scores on the Hamilton scale (40% decrease), but no difference between the group receiving sham TMS and real.
This result leads us to question whether or not EMT would have only a placebo effect. http://www.thestudentroom.co.uk/showthread.php?t=2551451

With major depression pharmacologically resistant

Another finding of the study was an improvement in the subject's performance on neuropsychological tests after 10 days of treatment.
 In the study, there was still a patient in response to greater than one year after the use of TMS 2) Studies with reduced EMT for use in the treatment of depression evident.
Subsequent to study Paschal-Leone et al [1996] George et al [1997] found only a 20% decrease in score on the Hamilton scale after application of TMS over the left prefrontal cortex.
Pad berg et al [1999] also found a small improvement (19% decrease in the Hamilton scale) after low frequency TMS and marginal effects after high-frequency TMS.  http://forums.dietpower.com/topic.asp?TOPIC_ID=3993
These two studies used a smaller number of those who have been successful stimuli.
Look et al [1999] found no difference between the groups that received sham TMS and real. George et al [1997], based on a placebo-controlled study, depressed patients randomly divided to receive for 2 weeks active TMS (800 pulses, 20 Hz, 80% LM) or 2 weeks of placebo TMS over the left prefrontal cortex.
The mean score on the Hamilton scale decreased by 20% in the treatment group and increased by 12% in the placebo group.
The modest effect found in this study may be due to the smaller number of stimuli applied (800 per session) compared to others who have used 2,000 stimuli per day [Paschal-Leone et al, 1996; Trigs et al, 1999].
Pad berg et al [1999], in a randomized, divided 24 patients with major depression pharmacologically resistant (at least three drugs) into three groups: placebo EMT, low frequency TMS (1 Hz) and high frequency (10Hz). http://forums.dietpower.com/topic.asp?TOPIC_ID=4087

Info about Antidepressant medications

The authors [Coca et al, 1996] believe that the antidepressant effect of TMS is intrinsic rather than a possible trigger for the action of antidepressant drugs.
Trigs et al [1999], in an open study of rams over the left prefrontal cortex 10 patients with drug-resistant major depression, daily sessions conducted EMT (2000 stimuli 20 Hz, 80% LM) for 10 days for each patient.  http://forum.dutchfitness.com/showthread.php?p=61627#post61627
Antidepressant medications were reduced and discontinued for a week before the start of TMS.
 The TMS treatment was associated with a significant improvement in mood, including a 41% reduction in HAM-D score and 40% in the BDI. Five patients could be classified as responders, defined by a reduction of at least 50% of the HAM-D after application of MTS.
The improvement in the BDI scale in 10 patients was still statistically significant after 3 months of application of EMT.
 Although this was an open study, without the use of placebo, all patients were resistant to drug therapy, in which two periods of 4 weeks with antidepressants had resulted in failure.
With TMS, all answered well without antidepressant.
Avery et al [1999], in a study of real and placebo TMS over the left prefrontal cortex in the treatment of 6 patients with pharmacologically resistant depression used the following paradigms: 80% LM 10 Hz with 1,000 pulses in 10 sessions over a period of 16 days.  http://forum.dutchfitness.com/showthread.php?p=61628#post61628
The selected patients had had failed at least two different types of antidepressant. Despite the small sample, the authors concluded that the improvement in the group receiving rTMS (down from 10.5 in Hamilton scale) were significant.