Antidepressant medications were maintained at a stable dose

Antidepressant medications were maintained at a stable dose. The stimulation was performed over the left prefrontal cortex. Patients received 250 pulses for five days at an intensity of 90% LM.
 Only the group that received low frequency TMS showed a small improvement in scores on the Hamilton scale - decrease of 19%.
The difference between these studies poor effects of high-frequency TMS to the previous best results could be due to methodological differences, i.e. fewer stimuli / day and total treatment time compared to previous studies with high frequency [Paschal-Leone et al, 1996, George et al, 1997; Trigs et al, 1999].  hunainnaeem01: http://www.fragrantica.com/board/viewtopic.php?pid=1665792#p1665792Another difference was the quality of the sample: Pad berg et al used very severe patients with pharmacologically resistant depression (3 patients had tried medication unsuccessfully), while in other studies such as the one conducted by Look et al [1999], patients had tried Only one drug without result.
 Look et al [1999], in a double blind study with 18 patients with pharmacologically resistant severe depression found different results from those previously published (discussed above).
 Patients were randomly divided into two groups: TMS of the left doors lateral prefrontal cortex (1500 pulses, 110Hz, 110% LM) and sham TMS.
 They showed a significant linear improvement after 2 weeks of treatment in scores on the Hamilton scale (40% decrease), but no difference between the group receiving sham TMS and real.
This result leads us to question whether or not EMT would have only a placebo effect. http://www.thestudentroom.co.uk/showthread.php?t=2551451