Depressed patients showed a significant improvement

Eight patients with unit polar depression and six healthy subjects underwent stimulation with the following paradigms: five sessions of 20 stimuli at 0.5 Hz, separated by a minute, for a total of 100 stimuli per day for eight sessions.
Depressed patients showed a statistically significant improvement in both scales applied
Inventory Beck Depression and Hamilton-D Klein et al [1999,] performed a similar protocol but with a larger sample (70 patients) divided into two groups: group treatment that received TMS over the right frontal lobe with the intensity of 110% LM in 10 sessions at 1 Hz with 120 stimuli each session, and the group with sham TMS. http://www.naturalmuscle.co.uk/forum/index.php?topic=2261.0
Patients who received TMS had great improvement in scores of depression scales compared with the placebo group.
Seventeen of the 32 patients in the real TMS group and only 32 in eight patients in the placebo group improved more than 50% in the Hamilton-D scale.
Increased activity in the right prefrontal lobe may be the one responsible for the decreased activity of the wolf left prefrontal depression.
One of the advantages of inhibiting the right frontal lobe with rather low TMS stimulation of the left prefrontal lobe with high frequency often is safety.
 It reduced the likelihood of low frequency TMS cause seizures, despite the high-frequency TMS still be acceptably safe [Ember et al, 1998]. http://www.hypermuscles.com/f89/how-gain-muscle-mass-using-forearms-rod-6913/#post33055
The effects of low frequency TMS in the right prefrontal cortex in major depression and psychotic are still unknown. These studies support the paradigm of unbalance of the prefrontal lobe in major depression. COULD INDUCE EMTR CRISIS OF BIPOLAR MANIA IN PATIENTS?